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24-HOUR MH HOTLINE

800-644-9737

FOR EMERGENCIES ONLY

24-HOUR MH HOTLINE: 800-644-9737
FOR EMERGENCIES ONLY

What is NMSIS?

NMSIS serves as an international resource center for knowledge on neuroleptic malignant syndrome in addition to other heat-related disorders and drug side effects by:

  1. Developing educational support programs
  2. Supporting clinical and new product research and development
  3. Implementing updated web-based and published materials
  4. Providing evidence-based informational and consultative services

NMSIS is entirely supported by contributed funds from members and their families, medical professionals and corporations.

The recognition, diagnosis and treatment of NMS and related hyperthermic disorders, is critical in avoiding morbidity and mortality. However, there is often a lack of sufficient data or consensus on the management of NMS, and practitioners are often confused by the baffling differential diagnosis of uncommon but serious NMS-like disorders.

To assist clinicians and advance consensus and understanding of NMS, the Neuroleptic Malignant Syndrome Information Service (NMSIS) was founded in 1997 by the Malignant Hyperthermia Association of the United States (MHAUS) in collaboration with a group of prominent experts with extensive experience in treating NMS. MHAUS expanded into this area due to its mission to become a world-wide source for clinical expertise in heat-related disorders.

History of NMSIS

On Nov. 21, 1996, a meeting was held at the Philadelphia County Medical Society to discuss the development of an association to foster the study and recognition of neuroleptic malignant syndrome or NMS.  NMS was first identified in the 1960s as a dangerous side effect of certain medications used mostly to treat patients suffering from psychosis.  However, this side effect was not well known and was often missed by practicing clinicians.

To assist clinicians and advance consensus and understanding of NMS, the Neuroleptic Malignant Syndrome Information Service (NMSIS) was founded in 1997 by the Malignant Hyperthermia Association of the United States (MHAUS) along with a group of prominent psychiatrists with extensive experience in researching and treating NMS.

NMSIS is endorsed by the American Psychiatric Association (APA) and the American Psychiatric Nurse Association (APNA), the Canadian Psychiatric Association and serves patients, families and medical professionals.  MHAUS expanded into this area in keeping with its mission to become a world-wide source for clinical expertise in heat-related disorders.

NMSIS has served as a unique, world-wide resource for information on NMS and related disorders.  In addition to its popular website, NMSIS has published numerous educational pamphlets and articles for patients and professionals.  NMSIS has also sponsored several regional and national scientific symposia to increase knowledge of NMS and promote patient safety.

The Shah Educational Awareness Fund was established in 2000 thanks to the generous support of the Shah family to help support educational outreach and further the mission of NMSIS to prevent morbidity and mortality from NMS. A popular family-oriented pamphlet was recently supported through a generous gift from the Speakman family.

Less than a decade since its inception, NMSIS continues its successful mission to research ways to educate patients and clinicians on NMS and related drug-induced disorders. 

Mission

The mission of NMSIS is to serve as an international resource center for educational and research initiatives to promote awareness, improve patient safety, and reduce morbidity and mortality in relation to heat-related disorders. These conditions are uncommon and may be unfamiliar to most practitioners, but can be encountered during the course of routine clinical practice in psychiatry and medicine.

Purpose

NMSIS is dedicated to reducing morbidity and mortality of NMS by improving medical and psychiatric care of patients with heat-related disorders; providing support information for medical professionals, patients and families, and improving scientific understanding of these conditions through research.

Goals

NMSIS has four primary goals:

  • Encourage and support research to determine the cause of NMS;
  • Advise and prepare all medical and psychiatric facilities for prompt diagnosis and immediate treatment of NMS;
  • Develop a standard NMS diagnosis and treatment protocol;
  • Promote awareness of NMS to help NMS patients and their families.
The mission of MHAUS is to promote optimum care and
scientific understanding of MH and related disorders.