[Image: masthead]

24-HOUR MH HOTLINE

800-644-9737

Outside NA: 001-209-417-3722
FOR EMERGENCIES ONLY

24-HOUR MH HOTLINE: 800-644-9737
Outside NA: 001-209-417-3722
FOR EMERGENCIES ONLY

Who Is Susceptible To MH?

There has been dramatic improvement in our understanding of what causes MH and who is at risk. Over 80 genetic defects have been associated with MH. MH susceptibility is inherited with an autosomal dominant inheritance pattern. This means that children and siblings of a patient with MH susceptibility usually have a 50% chance of inheriting a gene defect for MH, and hence would also be MH susceptible. They, therefore, may develop an MH reaction upon exposure to triggers.

Nevertheless, those who are carriers for susceptibility may be completely unaware of this risk unless they or a family member developed a life-threatening crisis during anesthesia. It is important to know that not everyone who has a gene defect linked to MH develops the MH crisis upon each exposure to the triggering anesthetics.

Testing for Malignant Hyperthermia
Testing

Information on Genetic and Muscle Biopsy testing for MH.

This item filed in the following categories:
  • Malignant Hyperthermia
The mission of MHAUS is to promote optimum care and
scientific understanding of MH and related disorders.