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24-HOUR MH HOTLINE

800-644-9737

Outside NA: 001-209-417-3722
FOR EMERGENCIES ONLY

24-HOUR MH HOTLINE: 800-644-9737
Outside NA: 001-209-417-3722
FOR EMERGENCIES ONLY

Blog

Blog

Regular updates by our President, MHAUS staff, and guest contributors.

The claims and opinions expressed in website blogs are those of the authors and not necessarily the views or opinions of MHAUS, its staff or its advertisers.

Best Wishes for the Holidays and New Year
Dr. Henry Rosenberg MD, CPE
December 28, 2011

At this joyous time of the year, I would like to wish all the friends and supporters of MHAUS best wishes for the holidays and the New Year. Your support and encouragement of our activities and programs motivates the entire team to continue to bring the latest information and educational programs to those with an interest in this complex, potentially fatal disorder first described over 50 years ago.

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"Awake" MH
Dr. Henry Rosenberg MD, CPE
November 21, 2011

From the beginning descriptions of the MH syndrome in the 1960s it was noted that the animal model for MH, i.e. certain pig breeds would develop muscle breakdown, acidosis, and high body temperature with stress alone (“awake MH”, i.e. MH signs without exposure to anesthetic agents).

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Thirtieth Anniversary of MHAUS
Dr. Henry Rosenberg MD, CPE
October 26, 2011

1981 was a rather important year in my professional life. On July first I assumed the Chairmanship of Anesthesiology at Hahnemann University in Philadelphia. In October 1981 the first meeting of what would turn out to be the founding Board of MHAUS met in my unfinished offices at Hahnemann.  It is hard to believe that thirty years have gone by which witnessed the evolution of a patient advocacy organization from an unknown entity to one where anyone seeking information and guidance on MH turns first.

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New Emergency Therapy for MH Poster
MHAUS Staff
October 1, 2011
Updates have been made to the Emergency Therapy for MH Poster effective September 2011.  Be prepared, order yours today! …
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2010 Scientific Conference Proceedings Ready
MHAUS Staff
September 30, 2011
This document is a collection of summaries prepared from information presented by the speakers at the MHAUS Scientific Conference held at the University of Pittsburgh’s Medical Center (UPMC), Mercy Hospital on April 23-24, 2010.
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Mount Dora mom launches campaign about rare condition a year after her son’s death
MHAUS Staff
September 30, 2011
Vincent Groetzner was a fun-loving 6-year-old who enjoyed soccer and painting when his body temperature suddenly skyrocketed to 108 degrees a year ago. His mother quickly raced him to a hospital emergency room, where he died within minutes.
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YouTube Rap on the Pathophysiology of Malignant Hyperthermia
MHAUS Staff
September 30, 2011
A rap song about Malignant Hyperthermia written by med students Nick and Brandon
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Muscle pain, muscle weakness and Malignant Hyperthermia. Is There a Connection?
Dr. Henry Rosenberg MD, CPE
September 26, 2011

Surprising revelations concerning the association of MH with Drug induced muscle pain; muscle weakness with age; and an inherited syndrome of muscle weakness.

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Overview of drug induced hyperthermic syndromes other than MH (Part A)
Dr. Henry Rosenberg MD, CPE
August 16, 2011

In this month’s blog, I have asked Dr. Stanley Caroff, Professor of Psychiatry at the University of Pennsylvania, a long time member of MHAUS and prolific author on the subject of Neuroleptic Malignant Syndrome (NMS) to summarize several drug related reactions that resemble MH in some ways but are generally thought to be unrelated to the mechanisms that lead to MH.

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Insuring Safer Anesthesia Care for MH-Susceptibles (or How Everything Old Is New Again)
MHAUS Staff
July 1, 2011

When an MH susceptible patient requires a general anesthetic one concern is whether he/she will be inadvertently exposed to potent gas anesthetics such as sevoflurane or isoflurane that may trigger an MH episode.

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The European MH Group Meeting
Dr. Henry Rosenberg MD, CPE
June 21, 2011

I was privileged to attend the 30th Annual European MH Group (EMHG) meeting in the town of Nijmegen, Holland from June 8-10 this year. The EMHG was developed in the early 1980s by a group of clinical anesthesiologists and researchers interested in advancing the understanding of MH and providing optimum care to MH susceptibles and their families. The EMHG has focused on testing for MH susceptibility, muscle biopsy contracture tests as well as genetic tests and their relation to biochemical and physiologic changes that underlie the MH syndrome.

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An Overview of the First ever MH Hotline/Professional Advisory Council Meeting
Dr. Henry Rosenberg MD, CPE
May 31, 2011

On May 14, 2011 MHAUS sponsored the first ever day long retreat for our hotline and professional advisory consultants. 30 consultants, including one board member (Debra Merritt), a genetic counselor associated with the University of Pittsburgh MH DNA testing center (Deanna Steele) and Dr. Albert Urwyler, head of the MH testing center in Basel, Switzerland and member of the European MH group, met in a hotel near the Chicago O’Hare airport to discuss many perplexing issues related to MH.

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MHAUS is a Patient Safety Organization!
Dr. Henry Rosenberg MD, CPE
March 14, 2011

As part of my “day job” I am in charge of graduate medical education (i.e. residency programs) as well as medical student education at a large academic medical center.  In that capacity I and my colleagues who are supervising educational programs are required to keep up with the evolving standards that govern the training of the physicians of the future.

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The Doctor’s Dilemma-Part 2
Dr. Henry Rosenberg MD, CPE
February 18, 2011

Last month I discussed the difficulty of understanding how MH susceptibility relates to heat stroke, muscle breakdown with exercise and MH without anesthesia. This is an exceedingly complex and murky topic.

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The Doctor’s Dilemma
Dr. Henry Rosenberg MD, CPE
January 6, 2011

On behalf of MHAUS, its Board, Staff, Professional Advisory Council, and Hotline Consultants I would like to wish all of you a Happy and Healthy New Year. Our hope for the future is to fulfill the mission of eliminating death and disability related to MH and MH-related syndromes.

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2010: A Year of Accomplishments for MHAUS
MHAUS Staff
December 1, 2010

Earlier this year I described what lies ahead for MHAUS. I laid out an ambitious program for the year.  I am pleased to report that with one or two exceptions the goals were largely met. Here are some of the programs and accomplishments of 2010:

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Some New and Interesting Developments
Dr. Henry Rosenberg MD, CPE
November 10, 2010

First, I would like to apologize for the somewhat technical blog I posted for October, 2010. I realize that not everyone would be familiar enough with the science of MH and cellular physiology to understand some of the information behind my reasoning. However, in basic terms what I was trying to do was separate MH into subcategories based on what is known of the molecular biology and biochemistry of the disorder.  I realize too that not everyone would agree with my reasoning, but that is what a blog is for, i.e., theorizing and proposing some new ways of looking at things. 

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Towards a definition and classification of MH and MH-like syndromes
Dr. Henry Rosenberg MD, CPE
October 28, 2010

Malignant Hyperthermia (MH) is a life threatening syndrome characterized by hypermetabolism, hyperthermia, acidosis, muscle contraction, muscle membrane breakdown, hyperkalemia and rhabdomyolysis. The syndrome occurs as a result of exposure to certain drugs and /or environmental conditions.

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What More Is there to Learn about Malignant Hyperthermia?
Dr. Henry Rosenberg MD, CPE
September 30, 2010

On September 20, 2010 I had the privilege of being a visiting professor at the University of Colorado, Denver Medical School and delivering the annual Hermann B. Stein MD, endowed lecture. Dr. Stein practiced anesthesiology in Denver for many years in the 1920s, 30s and 40s. His son then became an anesthesiologist and practiced the specialty for close to 40 years. One of his daughters is now a practicing anesthesiologist in New England.  Three generations of anesthesiologists. Pretty striking.

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Further thoughts on the Definition of MH
Dr. Henry Rosenberg MD, CPE
August 13, 2010

Over the past several months, since our April scientific conference, I have been thinking about the question “How should we define MH”?  Sounds like a pretty straightforward question, but in reality it is quite complex.

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The mission of MHAUS is to promote optimum care and
scientific understanding of MH and related disorders.