Blog - MHAUS

Regular updates by our President, MHAUS staff, and guest contributors.

The claims and opinions expressed in website blogs are those of the authors and not necessarily the views or opinions of MHAUS, its staff or its advertisers.

Dantrolene May Help Fight Duchenne Muscular Dystrophy: MHAUS Staff
December 14, 2012: This excerpt is from a Science Daily post on a recent article in the in the peer-reviewed journal Science Translational Medicine, "Dantrolene Enhances Antisense-Mediated Exon Skipping in Human and Mouse Models of Duchenne Muscular Dystrophy." Click here to read more. Drugs are currently being tested that show promise in treating patients …; Comments (0)

Estimate of the Relative Risk of Succinylcholine for Triggering Malignant Hyperthermia: MHAUS Staff
December 11, 2012: The paper "Estimate of the Relative Risk of Succinylcholine for Triggering Malignant Hyperthermia" written by: Franklin Dexter, MD, PhD*, Richard H. Epstein, MD, CPHIMS , Ruth E. Wachtel, PhD, MBA, and Henry Rosenberg, MD has been posted on the website for Anesthesia & Analgesia. Click here to see the entire post. Abstract BACKGROUND: …; Comments (2)

Do you know what Malignant Hyperthermia is? I know I Didn't: MHAUS Staff
December 10, 2012: Mrs. Joseph Wood recently commented on her son's susceptibility to Malignant Hyperthermia in a December 9 post "When your travels take unexpected turns God remains faithful!" on her Blog "A Moment with M.O.M." Read the full article. It was 10:30 on Friday night when we finally pulled into Topeka, Our semi …; Comments (1)

Succinylcholine for Triggering Malignant Hyperthermia: MHAUS Staff
December 8, 2012: Estimate of the Relative Risk of Succinylcholine for Triggering Malignant Hyperthermia This abstract was published by Anesthesia & AnalgesiaÂ and written by: Franklin Dexter, MD, PhD*, Richard H. Epstein, MD, CPHIMS , Ruth E. Wachtel, PhD, MBA, and Henry Rosenberg, MD. From the *Division of Management Consulting, Department of Anesthesia, University of Iowa, …; Comments (1)

New abstract on the sarcolemmal cation channel announced: MHAUS Staff
November 30, 2012: New abstract relating to Malignant Hyperthermia announced on PubMed. Nonspecific sarcolemmal cation channels are critical for the pathogenesis of malignant hyperthermia. link to PubMed article. Eltit JM, Ding X, Pessah IN, Allen PD, Lopez JR. Source *Department of Physiology and Biophysics, Virginia Commonwealth University, Richmond, Virginia, USA; Abstract Malignant hyperthermia …; Comments (0)

How likely are severe reactions to anesthesia ?: MHAUS Staff
November 29, 2012: From Ask Doctor K. - Dr. Anthony Komaroff, Harvard Medical School - In Association with Harvard Health Publications - Posted October 16, 2012, 2:13 PM link to article. DEAR DOCTOR K: I'm scheduled to have surgery soon, and I have never been under general anesthesia. How can I be …; Comments (2)

Surgical Anesthesia Students Build Online MH Flashcards: MHAUS Staff
November 29, 2012: The Surgery Technology Class of 2013 of Renton Technical College, Renton, Washington built online MH flashcards online using Quizlet to help study the drugs and medical terminology associated with Malignant Hyperthermia. Click this link to see the flash cards. Malignant Hyperthermia - Drugs & Purposes of The Surgical Technologist program …; Comments (0)

Lessons from the MH Hotline: MHAUS Staff
November 29, 2012: Lessons from the MH Hotline by MHAUS President Henry Rosenberg, MD I would like to wish all of our friends and supporters a happy and joyous holiday season. Although there are numerous and very threatening problems in the world today, we also have a lot to be thankful for as well.; Comments (0)

Scientists go the whole hog in genome mapping: MHAUS Staff
November 28, 2012: By Chris Wickham Reuters Wed, Nov 14, 2012 - link to story LONDON (Reuters) - Scientists have mapped the genome of the domestic pig in a project that could enhance the animal's use for meat production and the testing of drugs for human disease. Reuters/Reuters - A sow rests with …; Comments (0)

MH-Susceptible Can Donate A Kidney to Grandmother: MHAUS Staff
November 27, 2012: Here is an excerpt from Dayton Daily story "Readers share their thanks for holiday" written by News Staff Writer Mary McCarty, click here to read the full story. Kate Cleary of New Carlisle is thankful that she can donate a kidney to her grandmother, Shirley King of Middletown. "I am not …; Comments (0)

Patricia Belle Sparlin Gronert Memorial Fund: MHAUS Staff
November 26, 2012: Patricia Belle Sparlin Gronert, March 22, 1936 to October 31, 2012. She was born in Miles City, Montana; her mother and father owned and farmed wheat on a section of land a mile southwest of Brusett, MT. Pat's maternal grandmother (Lay's) was from Kirksville, MO (northeastern MO - northern influence) and …; Comments (0)

Malignant Hyperthermia Hotline Celebrates 30-Years: MHAUS Staff
October 11, 2012: MHAUS Hotline Celebrates Thirty Years of Service to the Community By MHAUS President Henry Rosenberg, MD A Brief History of the MH Hotline Shortly after MHAUS was formed in 1981 and the basic outline of the mission and vision of the organization was enunciated, the question of helping clinicians deal …; Comments (1)

Meet Malignant Hyperthermia Experts in Livingston, NJ Saturday 11-10-12: MHAUS Staff
October 1, 2012: The Malignant Hyperthermia Conference is for patients, healthcare professionals, students, and family, families and the public interested in the basics on how recognize, diagnose, and treat MH. The inherited muscle disorder Malignant Hyperthermia (MH) is most often triggered by certain anesthetic drugs leading to a life-threatening crisis that requires …; Comments (0)

Another Unusual and Disturbing Malignant Hyperthermia Death: MHAUS Staff
June 25, 2012: A few months ago, I received an unusual call from the MH Hotline who connected me to an anesthesiologist and OR team who were desperately trying to manage a Malignant Hyperthermia crisis. They were frantic and clearly trying to stabilize a patient experiencing a severe MH episode. The patient was an athletic older teenager undergoing an elective orthopedic surgical procedure on the ankle. Anesthesia was being conducted with the commonly used gas anesthetic sevoflurane and Succinylcholine had not been used.; Comments (30)

Succinylcholine Dantrolene Controversy: MHAUS Staff
May 30, 2012: Succinylcholine (also called Anectine) is a drug that has been in use for over half a century by anesthesia providers, emergency medicine physicians, critical care physicians and others when they wish to produce paralysis that is rapid in onset but lasts for only a few minutes.; Comments (12)

Comment on Mitochondrial Myopathy and Malignant Hyperthermia: MHAUS Staff
May 9, 2012: Topic: Does Mitochondrial Myopathy (MM) Increase an Individual's Susceptibility to Malignant Hyperthermia (MH) Please Comment on the Following Recommendations by June 9, 2012 Review of literature does not indicate an increased susceptibility to MH by patients diagnosed with Mitochondrial Myopathy (MM). Patients suffering from MM should receive an anesthetic …; Comments (0)

MH Experts Share Their Knowledge and Expertise Around the World: MHAUS Staff
April 24, 2012: The World Congress of Anesthesia is a meeting of anesthesiologists representing many countries that convenes in a different country every four years.; Comments (1)

The Role of DNA testing in Diagnosis of MH Prospects and Pitfalls: MHAUS Staff
March 1, 2012: In recent years, as DNA testing for diagnosis of many disorders has grown rapidly thanks to scientific advances, there has been a profusion of laboratories offering DNA testing to both the medical profession as well as the public. Although there are a few disorders where DNA testing of specific genes and specific mutations will predict susceptibility to a disorder, the problem for most inherited disorders is that all the DNA changes associated with the disorder have yet to be discovered.; Comments (0)

Grey’s Anatomy and a Potpourri of other News: MHAUS Staff
January 24, 2012: In the episode, the young patient undergoing emergency surgery develops elevated levels of carbon dioxide, increased heart rate and elevated temperature. The anesthesiologist recognizes the signs and informs the team of the problem. One of the OR personnel is dispatched to obtain ice and the anesthesiologist whips out a vial of dantrolene, injects it and waits for the signs of MH to respond.; Comments (3)

A New Drug for Heat Stroke? Implications for Malignant Hyperthermia: MHAUS Staff
January 12, 2012: While their common triggers may differ, the signs associated with MH and heat stroke are remarkably similar – uncontrolled muscle contractions, dangerous increases in body temperature, and muscle breakdown leading to the release of toxins in the blood which may cause cardiac arrhythmias and death.; Comments (0)

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