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24-HOUR MH HOTLINE

800-644-9737

FOR EMERGENCIES ONLY

24-HOUR MH HOTLINE: 800-644-9737
FOR EMERGENCIES ONLY

Blog

Blog

Regular updates by our President, MHAUS staff, and guest contributors.

Malignant Hyperthermia Hotline Celebrates 30-Years
MHAUS Staff
October 11, 2012
MHAUS Hotline Celebrates Thirty Years of Service to the Community By MHAUS President Henry Rosenberg, MD A Brief History of the MH Hotline Shortly after MHAUS was formed in 1981 and the basic outline of the mission and vision of the organization was enunciated, the question of helping clinicians deal …
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Meet Malignant Hyperthermia Experts in Livingston, NJ Saturday 11-10-12
MHAUS Staff
October 1, 2012
The Malignant Hyperthermia Conference is for patients, healthcare professionals, students, and family, families and the public interested in the basics on how recognize, diagnose, and treat MH.   The inherited muscle disorder Malignant Hyperthermia (MH) is most often triggered by certain anesthetic drugs leading to a life-threatening crisis that requires …
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Another Unusual and Disturbing Malignant Hyperthermia Death
MHAUS Staff
June 25, 2012

A few months ago, I received an unusual call from the MH Hotline who connected me to an anesthesiologist and OR team who were desperately trying to manage a Malignant Hyperthermia crisis. They were frantic and clearly trying to stabilize a patient experiencing a severe MH episode. The patient was an athletic older teenager undergoing an elective orthopedic surgical procedure on the ankle. Anesthesia was being conducted with the commonly used gas anesthetic sevoflurane and Succinylcholine had not been used.

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Succinylcholine Dantrolene Controversy
MHAUS Staff
May 30, 2012
Succinylcholine (also called Anectine) is a drug that has been in use for over half a century by anesthesia providers, emergency medicine physicians, critical care physicians and others when they wish to produce paralysis that is rapid in onset but lasts for only a few minutes.
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Comment on Mitochondrial Myopathy and Malignant Hyperthermia
MHAUS Staff
May 9, 2012
Topic: Does Mitochondrial Myopathy (MM) Increase an Individual's Susceptibility to Malignant Hyperthermia (MH)   Please Comment on the Following Recommendations by June 9, 2012 Review of literature does not indicate an increased susceptibility to MH by patients diagnosed with Mitochondrial Myopathy (MM). Patients suffering from MM should receive an anesthetic …
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MH Experts Share Their Knowledge and Expertise Around the World
MHAUS Staff
April 24, 2012

The World Congress of Anesthesia is a meeting of anesthesiologists representing many countries that convenes in a different country every four years.

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The Role of DNA testing in Diagnosis of MH Prospects and Pitfalls
MHAUS Staff
March 1, 2012
In recent years, as DNA testing for diagnosis of many disorders has grown rapidly thanks to scientific advances, there has been a profusion of laboratories offering DNA testing to both the medical profession as well as the public. Although there are a few disorders where DNA testing of specific genes and specific mutations will predict susceptibility to a disorder, the problem for most inherited disorders is that all the DNA changes associated with the disorder have yet to be discovered.
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Grey’s Anatomy and a Potpourri of other News
MHAUS Staff
January 24, 2012

In the episode, the young patient undergoing emergency surgery develops elevated levels of carbon dioxide, increased heart rate and elevated temperature. The anesthesiologist recognizes the signs and informs the team of the problem.  One of the OR personnel is dispatched to obtain ice and the anesthesiologist whips out a vial of dantrolene, injects it and waits for the signs of MH to respond.

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A New Drug for Heat Stroke? Implications for Malignant Hyperthermia
MHAUS Staff
January 12, 2012
While their common triggers may differ, the signs associated with MH and heat stroke are remarkably similar – uncontrolled muscle contractions, dangerous increases in body temperature, and muscle breakdown leading to the release of toxins in the blood which may cause cardiac arrhythmias and death.
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'Couch Potato' Pill Prevents Heat Stroke, Study Finds
MHAUS Staff
January 9, 2012
Scientists have stumbled upon a drug that may prevent heat stroke for people prone to the deadly condition. Ironically, it’s the same drug flaunted three years ago as the “couch potato pill” for its ability to build muscle and increase endurance in mice that never break a sweat.
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Best Wishes for the Holidays and New Year
Dr. Henry Rosenberg MD, CPE
December 28, 2011

At this joyous time of the year, I would like to wish all the friends and supporters of MHAUS best wishes for the holidays and the New Year. Your support and encouragement of our activities and programs motivates the entire team to continue to bring the latest information and educational programs to those with an interest in this complex, potentially fatal disorder first described over 50 years ago.

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"Awake" MH
Dr. Henry Rosenberg MD, CPE
November 21, 2011

From the beginning descriptions of the MH syndrome in the 1960s it was noted that the animal model for MH, i.e. certain pig breeds would develop muscle breakdown, acidosis, and high body temperature with stress alone (“awake MH”, i.e. MH signs without exposure to anesthetic agents).

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Thirtieth Anniversary of MHAUS
Dr. Henry Rosenberg MD, CPE
October 26, 2011

1981 was a rather important year in my professional life. On July first I assumed the Chairmanship of Anesthesiology at Hahnemann University in Philadelphia. In October 1981 the first meeting of what would turn out to be the founding Board of MHAUS met in my unfinished offices at Hahnemann.  It is hard to believe that thirty years have gone by which witnessed the evolution of a patient advocacy organization from an unknown entity to one where anyone seeking information and guidance on MH turns first.

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New Emergency Therapy for MH Poster
MHAUS Staff
October 1, 2011
Updates have been made to the Emergency Therapy for MH Poster effective September 2011.  Be prepared, order yours today! …
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2010 Scientific Conference Proceedings Ready
MHAUS Staff
September 30, 2011
This document is a collection of summaries prepared from information presented by the speakers at the MHAUS Scientific Conference held at the University of Pittsburgh’s Medical Center (UPMC), Mercy Hospital on April 23-24, 2010.
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Mount Dora mom launches campaign about rare condition a year after her son’s death
MHAUS Staff
September 30, 2011
Vincent Groetzner was a fun-loving 6-year-old who enjoyed soccer and painting when his body temperature suddenly skyrocketed to 108 degrees a year ago. His mother quickly raced him to a hospital emergency room, where he died within minutes.
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YouTube Rap on the Pathophysiology of Malignant Hyperthermia
MHAUS Staff
September 30, 2011
A rap song about Malignant Hyperthermia written by med students Nick and Brandon
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Muscle pain, muscle weakness and Malignant Hyperthermia. Is There a Connection?
Dr. Henry Rosenberg MD, CPE
September 26, 2011

Surprising revelations concerning the association of MH with Drug induced muscle pain; muscle weakness with age; and an inherited syndrome of muscle weakness.

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Overview of drug induced hyperthermic syndromes other than MH (Part A)
Dr. Henry Rosenberg MD, CPE
August 16, 2011

In this month’s blog, I have asked Dr. Stanley Caroff, Professor of Psychiatry at the University of Pennsylvania, a long time member of MHAUS and prolific author on the subject of Neuroleptic Malignant Syndrome (NMS) to summarize several drug related reactions that resemble MH in some ways but are generally thought to be unrelated to the mechanisms that lead to MH.

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Insuring Safer Anesthesia Care for MH-Susceptibles (or How Everything Old Is New Again)
MHAUS Staff
July 1, 2011

When an MH susceptible patient requires a general anesthetic one concern is whether he/she will be inadvertently exposed to potent gas anesthetics such as sevoflurane or isoflurane that may trigger an MH episode.

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The mission of MHAUS is to promote optimum care and
scientific understanding of MH and related disorders.