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MHAUS Blog

Draft Recommendation: EHI and MH

by Guest Contributor

Wednesday, June 21, 2017 /

Tagged: For Public Comment ·

What is the relationship between malignant hyperthermia susceptibility and heat or exercise related rhabdomyolysis? (developed by Dr. Stacey Watt) Background It has long been known that there exists an poorly-defined relationship between MH susceptibility and the development of a non-anesthetic MH-like illness during conditions of heat, exercise, stress, or viral …

0 Comments · 867 words · est. read time: 4 minutes · Read and Comment »

Draft Recommendation: Dr. Lena Mayes

by Guest Contributor

Wednesday, June 7, 2017 /

Tagged: For Public Comment ·

Topic Can patients with a suspected personal or family history of MH be safely anesthetized prior to diagnostic testing? (developed by Dr. Lena Mayes) Background Patients with a suspected personal or family history of MH are often denied access to general anesthesia prior to diagnostic testing, resulting in cancellation and …

9 Comments · 1302 words · est. read time: 7 minutes · Read and Comment »

Draft Recommendation: Dr. Cynthia Wong

by Guest Contributor

Wednesday, June 7, 2017 /

Tagged: For Public Comment ·

Topic Following treatment of acute MH, how much dantrolene should be administered and for how long? What criteria should be used to determine stopping treatment with dantrolene? (developed by Dr. Cynthia Wong) Background Following initial successful treatment of acute MH, MHAUS currently recommends continuing dantrolene therapy for at least 24 …

1 Comment · 319 words · est. read time: 2 minutes · Read and Comment »

MH Readiness Feedback from Multiple Facilities

by Dianne Daugherty, MHAUS Executive Director

Monday, April 17, 2017 /

Tagged: General ·

The only requirement the Malignant Hyperthermia Association of the United States (MHAUS) will not waiver on is this:  Any facility using a trigger for malignant hyperthermia (potent volatile anesthetics and/or succinylcholine) must assure there is a sufficient supply of dantrolene sodium for injection available within 10 minutes, in whatever form …

0 Comments · 656 words · est. read time: 3 minutes · Read and Comment »

Long-term Sequelae In Patients Who Experienced a Malignant Hyperthermia Event

by MHAUS Staff

Tuesday, December 13, 2016 /

Tagged: For Patients ·

Werneid K, Riazi S, Brandom BW. Presented to the International Anesthesia Research Society (IARS) 2015 In the article Survey of Long-Term Sequelae in Survivors of a Malignant Hyperthermia Reaction, 23 people responded to a survey asking about the symptoms they experienced after an MH event. The most commonly reported symptoms …

4 Comments · 136 words · est. read time: 1 minute · Read and Comment »

Unexpected MH Deaths Without Exposure To Inhalation Anesthetics In Pediatric Patients

by MHAUS Staff

Tuesday, December 13, 2016 /

Tagged: For Patients ·

Brandom, BW, & Muldoon, SM. Paediatric Anaesthesia . September 2013. It is well documented that infants, children and adolescents with certain gene mutations are susceptible to malignant hyperthermia when exposed to certain medications including succinylcholine, a muscle relaxant, and inhalation anesthetics. However, fatal, MH-like episodes have also been documented in …

4 Comments · 213 words · est. read time: 1 minute · Read and Comment »

Temperature changes are not late signs of malignant hyperthermia: A NAMH Registry of MHAUS Study

by Guest Contributor

Tuesday, December 13, 2016 /

Tagged: For Patients ·

Temperature changes are not late signs of malignant hyperthermia: A NAMH Registry of MHAUS Study. Larach MG, Allen GC, Brandom BW, Gronert GA, & Lehman EB. Presented to the American Society of Anesthesiologists (ASA), 2008 Malignant hyperthermia poses a significant risk to affected patients. Despite modern treatment and increased availability …

2 Comments · 207 words · est. read time: 1 minute · Read and Comment »

Is there a link between malignant hyperthermia and exertional heat illness?

by Guest Contributor

Tuesday, December 13, 2016 /

Tagged: For Patients ·

Muldoon SM, Deuster P, Brandom BW, Bunger R. Exercise and Sport Sciences Reviews, 2004 It has been suggested that people who have experienced an episode of exertional heat illness may be more prone to malignant hyperthermia and vice versa due to a similar genetic mutation. Malignant hyperthermia (MH) is an …

1 Comment · 425 words · est. read time: 2 minutes · Read and Comment »

Intraoperative Presentation of MH Leads To KD Syndrome Diagnosis

by MHAUS Staff

Thursday, December 8, 2016 /

Tagged: General ·

Abstract: We present the novel case report of a child with hypotonia and dysmorphic features who developed malignant hyperthermia (MH) intraoperatively. Neurology workup revealed the presence of a known causative ryanodine receptor (RYR1) mutation for MH, c.7522C>T; p.R2508C. Furthermore, the neurology workup diagnosed the child with King-Denborough syndrome (KDS). This …

0 Comments · 126 words · est. read time: 1 minute · Read and Comment »

Long Term Oral Dantrolene Improved Muscular Symptoms in a Malignant Hyperthermia Susceptible Individual

by Guest Contributor

Thursday, November 17, 2016 /

Tagged: For Patients ·

Unexpected MH deaths without exposure to inhalation anesthetics in pediatric patients. Brandom, BW, & Muldoon, SM. Paediatric Anaesthesia. September 2013. It is well documented that infants, children and adolescents with certain gene mutations are susceptible to malignant hyperthermia when exposed to certain medications including succinylcholine, a muscle relaxant, and inhalation …

0 Comments · 1146 words · est. read time: 6 minutes · Read and Comment »


 

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