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Safe and Unsafe Anesthetics

Not safe for use in MH-susceptible patients, the following anesthetic agents are known triggers of MH:

  • Inhaled General Anesthetics
  • Desflurane
  • Enflurane
  • Ether
  • Halothane
  • Isoflurane
  • Methoxyflurane
  • Sevoflurane
  • Succinylcholine (warning)

All other anesthetic agents outside of these two categories of Volatile anesthetic agents and depolarizing muscle relaxants are considered safe.

Safe Anesthetic Agents for MH Patients:

Barbiturates / Intravenous Anesthetics

  •  Diazepam
  •  Etomidate (Amidate)
  •  Hexobarbital
  •  Ketamine (Ketalar)
  •  Methohexital (Brevital)
  •  Midazolam
  •  Pentobarbital
  •  Propofol (Diprivan)
  •  Thiopental (Pentothal)

Inhaled Non-Volatile General Anesthetic

  • Nitrous Oxide

Local Anesthetics

  • Amethocaine
  • Articaine
  • Bupivicaine
  • Dibucaine
  • Etidocaine
  • Eucaine
  • Lidocaine (Xylocaine)
  • Levobupivacaine
    Mepivicaine (Carbocaine)
    Procaine (Novocain)
  • Prilocaine (Citanest)
  • Ropivacaine
  • Stovaine
  • Proparacaine Hydrochloride ALCAINE®
    (proparacaine hydrochloride ophthalmic solution) 

Narcotics (Opioids)

  • Alfentanil (Alfenta)
  • Anileridine
  • Codeine (Methyl Morphine)
  • Diamorphine
  • Fentanyl (Sublimaze)
  • Hydromorphone (Dilaudid)
  • Meperidine (Demerol)
  • Methadone
  • Morphine
  • Naloxone
  • Oxycodone
  • Phenoperidine
  • Remifentanil
  • Sufentanil (Sufenta)

Safe Muscle Relaxants

  • Arduan (Pipecuronium)
  • Curare (The active ingredient is Tubocurraine)
  • Gallamine
  • Methocarbamol (Robaxin, Robaxin-750, Carbacot, Skelex)
  • Metocurine
  • Mivacron (Mivacurium)
  • Neuromax (Doxacurium)
  • Nimbex (Cisatracurium)
  • Norcuron (Vecuronium)
  • Pavulon (Pancuronium)
  • Tracrium (Atracurium)
  • Zemuron (Rocuronium)

Anxiety Relieving Medications

  •  Ativan (Lorazepam)
  •  Centrax
  •  Dalmane (Flurazepam)
  •  Halcion (Triazolam)
  •  Klonopin
  •  Librax
  •  Librium (Chlordiazepoxide)
  •  Midazolam (Versed)
  •  Paxil (paroxetine)
  •  Paxipam (Halazepam)
  •  Restoril (Temazepam)
  •  Serax (Oxazepam)
  •  Tranxene (Clorazepate)
  •  Valium (Diazepam)

 

 

 

 

 

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