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24-HOUR MH HOTLINE

800-644-9737

Outside NA: 001-209-417-3722
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24-HOUR MH HOTLINE: 800-644-9737
Outside NA: 001-209-417-3722
FOR EMERGENCIES ONLY

Is dantrolene (the antidote for MH) considered safe to use in obstetrics should an MH episode occur?

While dantrolene can be given to a pregnant woman, it does cross the placenta and there are side effects in the neonate. This again is just a risk and would have to be weighed against the expected benefit. Weakness in the neonate might be expected and must be looked for and treated appropriately. An article published in 1988 suggests that at low dose, there are no problems. (Am J Obstet Gynecol., Oct 1988;159(4):831-4.

This item filed in the following categories:
  • Dantrolene
  • MH and Pregnancy
The mission of MHAUS is to promote optimum care and
scientific understanding of MH and related disorders.